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The review will add to the existing literature by showing compelling evidence and improved guidance in clinic settings. 10.17605/OSF.IO/7N8RY. 10.17605/OSF.IO/7N8RY. HOXB7 is abnormally expressed in a variety of tumors, but its prognostic value remains unclear due to sample size limitation and outcome inconsistency in previous studies. This meta-analysis was performed to explore the effect of HOXB7 expression on prognoses and clinicopathological factors in range of the whole solid tumors. PubMed, EMBASE, and Web of Science databases wer