https://www.selleckchem.com/pr....oducts/GSK1904529A.h
This study aimed to investigate the effects of miR-29b on renal interstitial fibrosis in the obstructed kidney of mouse with unilateral ureteral obstruction (UUO) via inhibiting phosphatidylinositol 3-kinase/protein kinaseB (PI3K/AKT) signaling pathway. Adult male CD-1 mice were intraperitoneally injected with vehicle or PI3K inhibitor LY294002 (3mg/kg, 30mg/kg) daily for 1 or 2weeks after performing UUO or sham operation. The mice were sacrificed on days 7 and 14 after surgery. The rat proximal tubular epithelial cell (TEC) line NR
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