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Two Bulbine species and dietary supplements were clustered into different groups and possible chemical markers were identified. The developed analytical method provided a fast, economic method for quality assessment of Bulbine species in dietary supplements based on anthraquinone-type compounds. This study reports holistic chemical profiling of Bulbine species using LC- QToF. The analytical method developed enabled non-targeted analysis of components in B. natalensis and B. frutescens, recommending for commercial and regulatory purpose
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