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374 (95% CI 5.871∼127.636), 28.587 (95% CI 4.139∼197.46, and 4.315 (95% CI 0.858∼21.694), respectively. In the predictive model of PTC, the value of sensitivity, specificity, accuracy, and Youden index was 87.8%, 94.2%, 91.1%, and 0.82 with a likelihood ratio of 15.1. Therefore, the signs of an irregular ring, marginal defects, and enhanced blurring may be helpful in the diagnosis of PTC in incidentally found thyroid nodules. Globally, 1.2 billion people live in trachoma endemic areas, 40.6 million people are suffering from active tr