https://www.selleckchem.com/pr....oducts/o6-benzylguan
In this study, the molecular state of ritonavir (RTN)-saccharin (SAC) coamorphous incorporated into mesoporous silica by solvent evaporation and the effect of SAC on the RTN dissolution from mesopores were investigated. The amorphization of RTN-SAC was confirmed as a halo pattern in powder X-ray diffraction measurements and a single glass transition event in the modulated differential scanning calorimetry (MDSC) curve. 13C solid-state NMR spectroscopy revealed a hydrogen bond between the thiazole nitrogen of RTN and the amine p
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