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Overall, the proposed coating strategies allowed the deposition of a biocompatible nanostructured film onto the PI surface and could represent a valid tool to enhance long-term IfNI biocompatibility by improving tissue/electrode integration.Digital integrated circuits play an important role in the development of new information technologies and support Industry 4.0 from a hardware point of view. There is great pressure on electronics companies to reduce the time-to-market for product development as much as possible. The most time-consumi