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However, only 4 amino acids (alanine, glycine, methionine and tryptophan) were significantly recovered after BAWLo and BAWHi treatment. This study provides the first results pertaining to metabolic changes in the asthma model mice treated with OVA+BAW. Additionally, these findings show that 4 metabolites can be used as one of biomarkers to predict the anti-asthmatic effects. © The Author(s) 2019.Although the number of prescriptions and dependence on sleeping pills are increasing, the associations with unexpected abnormal behaviors and