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o families of OHCs, constituted most of the nonvolatile components in CPEO. The nonvolatiles contributed significantly to the in vitro antioxidant activity of CPEO. Pomelo CPEO showed good prospects as a potential long-lasting natural antioxidant. To assess the cellular and molecular effects of lidocaine on muscles/myoblasts. Cultured myogenic precursor (C2C12) cells were treated with varying concentrations of lidocaine. Cell viability of C2C12 cells was inhibited by lidocaine in a concentration-dependent manner, with concentrations ≥0
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