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ADHD in Adults Undiagnosed Living with a diagnosis of undiagnosed ADHD can be extremely difficult and can lead to years of shame and low self-esteem. This can cause depression, as well as other mental health issues, or even alcohol abuse. Unlike children who are diagnosed with ADHD, diagnosing ADHD in adults requires a thorough history that could include a psychological examination and a conversation with close family members for their perspectives on childhood behaviors. 1. Trouble in