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https://www.selleckchem.com/pr....oducts/mito-tempo.ht
An attempted Regitz diazo transfer onto homophthalic anhydride led to the discovery of an unexpected ring contraction, which gave N-sulfonyl phthalide-3-carboxamide derivatives. The reaction is thought to proceed via a [3 + 2] cycloaddition of the substrate's enol form and the azide followed by a two-step fragmentation of the intermediate 1,2,3-triazoline with a loss of the nitrogen molecule.Purpose Adolescents and young adults (AYAs) with cancer are in a unique situation due to their age and developmental stage in life and may have