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The results of the present study indicated that bFGF attenuates myocardial injury by inhibiting apoptosis and promoting angiogenesis a novel HIF-1α-mediated mechanism and a potential utility of bFGF in protecting against myocardial infarction. The results of the present study indicated that bFGF attenuates myocardial injury by inhibiting apoptosis and promoting angiogenesis via a novel HIF-1α-mediated mechanism and a potential utility of bFGF in protecting against myocardial infarction.Due to the complex visual environment and incomplete d