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This systematic literature review will help practitioners to take help from the existing literature and propose new solutions based on the available evidence in urban aquaponics.Interest in perchlorate as environmental pollutant has increased since 1997, when high concentrations have been found in the waters of the Colorado River, USA. Perchlorate is very persistent in nature and it is slowly degraded. Although harmful effects of large doses of perchlorate on thyroid function have been proven, the environmental effects are still unclear.