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Our laboratory has recently linked the chronic infection in diabetes to poor useful effects and exacerbated intellectual impairment, also called post-stroke cognitive impairment (PSCI). Although we have shown that the development of PSCI in diabetes is from the upregulation and also the activation of pro-inflammatory microglia, we have not founded direct causation between the two. For this end, we evaluated the role of microglia in the growth of PSCI. TECHNIQUES At 13 weeks of age, diabetic creatures