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811 and 0.834, respectively. The ratio of Th17/Treg exhibited the largest AUC of 0.897 (cutoff value 0.076).Conclusions Thus, the percentage of Th17 /Treg ratio of pediatric CITP is elevated at new diagnosed ITP stage. It is a promising predictive marker for the development of CITP to some extent.Trial registration ChiCTR1900022419 (10th April 2019) What is Known • The percentage of Th17 /Treg ratio of pediatric CITP is elevated. What is New • This study shows that the percentage of Th17 /Treg ratio of pediatric CITP is elevated at new di