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Such a mismatch might contribute to the decline of the smelt population in Lake IJsselmeer and Lake Markermeer. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.BACKGROUND AND PURPOSE Dopamine (DA) can protect the duodenal mucosa. The aim of the present study was to investigate the source of DA in gastric juice and the mechanism underlying the effects of luminal DA on duodenal bicarbonate secretion (DBS) in rodents. EXPERIMENTAL APPROACH Immunofluorescence, UPLC-MS/MS,