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https://www.selleckchem.com/pr....oducts/oicr-9429.htm
ention paradigm markedly increased expression of phosphorylated PI3K, AKT and GSK-3, but reduced phosphorylated β-catenin. Moreover, the axon guidance proteins expression level was significant higher in EE group. In parallel to these findings, EE significantly enhanced recovery of lost spatial learning memory function in MCAO rats without affecting infarct size. Together, MRI findings along with histological results strongly supported that the three-phase EE paradigm benefited neurovascular reorganization and thereby improved poststro