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© 2020 Deutsche Pharmazeutische Gesellschaft.AIMS to recognize and examine available proof from the effectiveness of personality strengths-based intervention from the emotional wellbeing of customers with persistent diseases. DESIGN A systematic analysis with meta-analysis. DATA SOURCES Six digital databases, including PubMed, EMBASE, EBSCO (CINAHL® and MEDLINE), Web of Science and PsycINFO, were looked from creation to December 2018. ASSESSMENT TECHNIQUES