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TGN4 also reduces the conformational transition of the Aβ1-42 monomer by means of interacting with the monomer. The present study presents molecular-level insights into how the TGN series of compounds affect the membrane adsorption and the conformational transition of the Aβ1-42 monomer, which could be valuable for the further development of new anti-Alzheimer agents.Bacteria belonging to the Rhodococcus genus are frequent components of microbial communities in diverse natural environments. Some rhodococcal species exhibit the outstanding