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https://www.selleckchem.com/pr....oducts/sp-600125.htm
nd that sex differences should be considered when developing miRNA biomarkers to diagnose or treat alcoholics.Mitochondria are controlled by the coordination of two genomes the mitochondrial and the nuclear DNA. As such, variations in nuclear gene expression as a consequence of mutations and epigenetic modifications can affect mitochondrial functionality. Conversely, the opposite could also be true. However, the relationship between mitochondrial dysfunction and epigenetics, such as nuclear DNA methylation, remains largely unexplored.