https://www.selleckchem.com/
Although the NSD mutant flies survived to adulthood, their fecundity was dramatically decreased. Furthermore, the NSD fly showed neurological dysfunctions, such as lower memory performance and motor defects, and a diminished extracellular signal-regulated kinase (ERK) activity. The NSD-deleted Drosophila phenotype resembles many of the phenotypes of SOTOS1 patients, such as learning disability, deregulated ERK signaling, and overgrowth; thus, this mutant fly is a relevant model organism to study various SOTOS1 phenotypes. The NSD-deleted Drosophila phenotyp
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