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https://www.selleckchem.com/pr....oducts/qnz-evp4593.h
The retinoblastoma binding protein RBP2 (KDM5A) is a histone demethylase that promotes cell growth in many human cancers. A series of functional experiments were conducted to explore the role of miR-421/KDM5A in ovarian cancer cells and their underlying molecular mechanisms. Public microarray databases were analyzed to assess KDM5A and miR-421 expression in ovarian cancer. KDM5A was predicted to be a target of miR-421 using software analysis. #link# The expression of the miR-421/KDM5A regulatory axis in ovarian cancer and the mechan