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No severe inflammation response was detected in the gross and microscopic appearance around the implants. CES and prucalopride treatment may yield similar short-term effects for improving gastrointestinal transit and stool consistency, and CES outperformed prucalopride treatment in terms of defecation inducement in the short term. There were ideal levels of endurance and histocompatibility for the animals that underwent CES. CES and prucalopride treatment may yield similar short-term effects for improving gastrointestinal transit and st