https://www.selleckchem.com/pr....oducts/all-trans-ret
Abiraterone acetate (AA) is a selective inhibitor of CYP17 α-hydroxylase which is crucial for androgen biosynthesis. Apigenin (Api) is a natural plant-derived flavonoid with potent antiproliferative and anti-migration effects. We aimed to investigate the possible role of Api in combination with the androgen receptor inhibitor AA in the treatment of androgen-sensitive human prostate cancer LNCaP cells. The cells were either exposed to 10 µM AA, 25 µM Api, or in combination for 48 hours, then the viability rate was determined by
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