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Therefore, the results obtained demonstrated (i) the Pseudomonas aeruginosa isolates were highly sensitive to INTP in-vitro, (ii) CFU reduction of infectious Pseudomonas in wounds of diabetic mice after INTP treatment is far superior to that of non-treated infected wounds, and (iii) the application of INTP shows no indication of toxic effects. Our results are consistent with indirect non-thermal atmospheric plasma as a promising adjunct to disinfecting wounds.Introduction Veno arterial membrane oxygenation (VA ECMO) is increasingly used