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malaria prevalence and incidence in communities where malaria prevalence was already low. Treatment coverage and adherence was very high. Results were strongly influenced by the lower-than-expected malaria prevalence, and by no clinical cases in villages with asymptomatic malaria-infected individuals. This study is registered with ClinicalTrials.gov, NCT02878200. Registered 25 August 2016. https//clinicaltrials.gov/ct2/show/NCT02878200 . This study is registered with ClinicalTrials.gov, NCT02878200. Registered 25 August 2016. https//clin