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OBJECTIVE The aim of this study was to develop specific prediction equations based on acceleration data measured at three body sites for estimating energy expenditure (EE) during static and active conditions in middle-aged and older adults with and without type 2 diabetes (T2D). RESEARCH METHODS Forty patients with T2D (age 40-74 yr, body mass index (BMI) 21-29.4 kg·m-2) and healthy participants (age 47-79 yr, BMI 20.2-29.8 kg·m-2) completed trials in both static conditions and treadmill walking. For all trials, gas exchange was monitore