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We discuss whether strains with additional virulence play a task in present EFB outbreaks.MicroRNAs tend to be regulators of gene expressionand may be key markers in liquid biopsy.Early diagnosis is an efficient way to increase patients' general survival. We produced genome-wide miRNA profiles from serum of customers and controls from the population-based Janus Serum Bank (JS and analysed all of them by bioinformatics and synthetic cleverness methods. JSB includes sera from 318