https://www.selleckchem.com/pr....oducts/GSK1904529A.h
To assess the effect of age on mechanisms of exercise tolerance. Prospective observational study recruited 71 healthy individuals divided into two groups according to their age i.e. younger (≤40years of age, N=43); and older (≥55years of age, N=28). All participants underwent maximal graded cardiopulmonary exercise stress testing using cycle ergometer with simultaneous non-invasive gas-exchange and central haemodynamic measurements. Using the Fick equation, arteriovenous O difference was calculated as the ratio between measured O co
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