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8 mL/year, 95% CI 9.3 to 30.3) (p for interaction=0.063). Exposure to indoor coal- or wood-burning stove heating (-79.4 mL, p less then 0.001) and secondhand smoke at home (-59.3 mL, p= 0.003) were inversely associated with FVC growth. Conclusion Our study raised serious alarm over the threat of severe air pollution to lung development in school-age children. Sex discrepancy in lung development was reduced dramatically in heavily polluted area.The pathology of sickle cell disease is caused by polymerization of the abnormal hemoglobin S u
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