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Usage of enzymatic removal treatments and analysis of hair for damage from harsh aesthetic remedies may help to independently determine and quantify the drugs included in the next two domains. Aims a) improvement an UPLC-MS/MS means for the simultaneous measurement regarding the after 19 antipsychotic drugs and metabolites in hair amisulpride, aripiprazole, chlorpromazine, clotiapine, clozapine, desmethylclozapine, desmethylolanzapine, haloperidol, norchlorpromazine, 7-OH-quetiapin