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The dose to the heart was slightly reduced in most patients. The median reduction in the mean heart dose was 0.22 Gy, and V was reduced by 2.5%.The maximum dose to the esophagus was also reduced in most patients, by 0.74 Gy, whereas V did not change significantly. The median number of points in which dose differences exceeded 3%/3 mm was 6.2%. Intra-fractional anatomical changes reduce PTV coverage compared to the coverage predicted by clinical treatment planning systems that use the average CT for dose calculation. Doses to organs at r
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