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Meanwhile, patients had significantly increased FC between the left caudate and OFC, and increased FC between the right putamen and fusiform. The mean FC value from the caudate-OFC, caudate-insula, and caudate-STP connectivity negatively correlated with the Premature Ejaculation Diagnostic Tool score, separately. Conclusion The current study showed the functional abnormality of lifelong PE in multiple brain regions implicated in sensation, motivation, and ejaculation-related inhibitory control, which may improve our understanding of the ab
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