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in pAAV should be reserved for uncertain cases where the diagnosis cannot be confirmed clinically and with serology. Left atrial appendage closure (LAAC) became an alternative method for stroke prevention in patients with non-valvular atrial fibrillation (AF) intolerant to long term oral anticoagulation therapy. This study aimed to compare endocardial (Amulet and LAmbere occluders) and epicardial (Lariat) LAAC techniques. A retrospective, observational case-control study included 223 consecutive CHA DS -VAS score-matched patients with A