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Authors, editors and peer-reviewers should make an effort to improve completeness and adequacy of Cochrane RoB assessment in non-Cochrane reviews. OBJECTIVES Classical meta-analyses routinely treated studies with no events in both arms non-informative and excluded them from analyses. This study assessed whether such studies contain information and have influence on the conclusions of meta-analyses. DESIGN and setting We collected meta-analyses of binary outcomes with at least one study having no events in both arms from Cochrane system
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