https://www.selleckchem.com/pr....oducts/defactinib.ht
Over time, scores improved statistically significant and clinically relevant in both arms. Between arms, there were no differences on any scale (range -3.8 to +4.. Scores on all scales were improved to a clinically relevant extent at 12 and 24 months compared to baseline in both arms, except for fatigue and motor dysfunction at 12 months (-7.4 and -8.8, respectively). In irradiated patients (N=59), scores in all preselected scales except motor dysfunction, remained stable up to 24 months compared to shortly after WBRT, overall mean
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