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leated syncytia. This extended growth time allows long term in vitro experimentation to further understand the nature of trophoblasts. Whether concomitant administration of anticancer agents influences the efficacy and safety of oral anticoagulants in patients treated for cancer-associated venous thromboembolism (VTE) is undefined. The pharmacological interaction between anticancer agents and direct oral anticoagulants is perceived as a concern. We evaluated the effects of concomitant administration of anticancer agents on recurrent VTE,