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Methods Relevant literature was searched in PubMed and EMBASE from creation to July 2019, for cohort studies that examined the relationships between renal rocks and these 3 diseases among grownups. Pooled general risks (RR) had been calculated by maximally modified risk estimates making use of a random effect design. Subgroup evaluation, meta-regression and sensitiveness analysis had been performed whenever appropriate. Outcomes of 3537 papers, 21 articles with every including 1-3 cohorts had been