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A general decrease in all presented cultures rates of 35% had been seen. This pattern had been seen across all centuries, including 2-5 month old babies. CONCLUSIONS PCV7/PCV13 execution lead to a marked and significant drop in pneumococcal, NTHi and total conjunctivitis rates in kids less then two years. The impact on NTHi episodes alludes to your part of pneumococcus-NTHi discussion in conjunctivitis. The effect in infants less then 6 months proposes herd protection. © The Author(s) 2