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Intimal hyperplasia in cardiac allograft vasculopathy (CAV ) is limiting survival in pediatric and adult patients after heart transplantation (HTx). Analysis of risk factors for CAV using the high resolution of intracoronary optical coherence tomography (OCT) is scarce, particularly in children, and recommendations for CAV prevention are largely based on data obtained in adults. Whether the predictive value of risk factors is age- or sex-dependent is unknown. We used OCT to test the age- and sex-dependency of established risk factors reg