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The RT-qPCR assays indicated that DS-SQ (101) could cure the PHZ-induced thrombosis by downregulating the expression of PKCα, PKCβ, fga, fgb, fgg and vWF in zebrafish. Conclusions DS-SQ with the combination ratio of 101 showed optimum anti-thrombotic effect on PHZ-induced zebrafish thrombosis model, which provided a reference for reasonable clinical applications of DS-SQ herbal pair. © The Author(s) 2020.Non-parametric and semi-parametric resampling procedures are widely used to perform support estimation in computational biology and b
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