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BACKGROUND Tumor vascular density and collagen matrix organization are critical factors to neoplasia development and progression. This study aimed to analyze the variables associated with the extracellular matrix in oral pleomorphic adenomas. METHODS This cross-sectional study comparatively evaluated 21 cases of pleomorphic adenomas and 21 sections of regular oral mucosa from the files of an oral pathology department. The tissue sections were subjected to immunohistochemical study with a monoclonal antibody specific to CD31 protein to a
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