https://www.selleckchem.com/pr....oducts/gsk-2837808A.
coli-infected macrophages. In a murine E. coli infection model, DPI effectively reduced ATP release, decreased bacterial load and inhibited inflammasome activation, thereby improving survival and ameliorating organ injuries in model mice. In summary, our study demonstrates a previously unknown function of DPI in conferring protection against bacterial infection and suggests a putative antimicrobial strategy of modulating CX43 -dependent ATP leakage.Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic debilitatin
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