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UV-Visible spectral evaluation reveals the current presence of proteins, nucleic acids and substance teams (ester, carbonyl, carboxyl and amine). Purified polysaccharides were light-green in shade plus in a form of odorless dust. It was dissolvable in water but insoluble in other organic solvents. Thermogravimetric analysis demonstrates that Chlorella vulgaris soluble polysaccharide is thermostable until 240°Ce tested for its antimicrobial activity and have results against Bacillus sp., Erwinia sp., Candi