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Rats exposed to repetitive low-level blasts gathered irregular hyperphosphorylated tau in neuronal perikarya and perivascular astroglial processes. Utilizing positron emission tomography (dog) additionally the [18F]AV1451 (flortaucipir) tau ligand, we found that five of 10 veterans exhibited excessive retention of [18F]AV1451 during the white/gray matter junction in front, parietal, and temporal mind regions, an average localization of CTE tauopathy.