https://www.selleckchem.com/pr....oducts/vx803-m4344.h
Thus, our results demonstrate that this partially humanized AgxtD205N rat strain is a high-performing model of primary hyperoxaluria type 1 for understanding pathology, and the development of novel therapeutics, such as reprogramming of the metabolic pathway through genome editing.Randomised Controlled Trials (RCTs) are considered the gold-standard for evaluating the effectiveness of interventions. However, criticisms of traditional designs are that they can be inefficient, inflexible, expensive and conducted in a manner disconnecte