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Zhi-Zi-Hou-Po Decoction (ZZHPD) has been used in clinical treatment of depression and relevant conditions for quite some time, in addition to potential poisonous damage caused by its long-lasting use has gradually emerged. Present research methods that expose toxicity by a one-time management of big doses cannot provide a reference for medical safe medicine usage. In this research, the potential toxicity of ZZHPD in repeated administration ended up being examined by urinary metabolomics with nondestructive sampl
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