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RESULTS The results showed significant inhibition of the production of NO and IL-10 and the expression of iNOS in all groups of mice in the presence of TAK-242. CONCLUSIONS These results presented evidence of the role of TLR-4/rBCG attachment mechanism in modulating the production of NO and IL-10 and the expression of iNOS in response to our rBCG-based malaria vaccine candidate expressing MSP-1C of P. falciparum. Copyright (c) 2019 Muhammad Adamu Abbas, Rapeah Suppian.INTRODUCTION Worldwide urban pigeons (Columba livia domestica) are an