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ADHD Medication The use of medication is usually a component of an ADHD treatment strategy. The two most commonly used stimulant medications are dextroamphetamine and methylphenidate. Each of them has a variety of brand names and each has a distinct chemical composition. Stimulants increase the levels of brain chemicals that help send messages between neurons. These are usually the first drugs doctors try for adults with ADHD. Stimulants Most doctors prescribe stimulants as the first