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Finding the Best Medication For ADHD The most frequently prescribed medication for ADHD is stimulants. They include methylphenidates and amphetamines. Short-acting stimulants begin to work in under an hour and must be taken multiple times per day. -acting stimulants last up to 16 hours and are taken every day. Your doctor may prescribe antidepressants, or other types medications "off-label" to treat ADHD symptoms. These drugs are approved to treat disorders such as anxiety and depression.
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