https://www.selleckchem.com/pr....oducts/nms-p937-nms1
Finally, combinatorial treatment with tamoxifen, TNFα and short-hairpin (sh)-NCOR1 resulted in enhanced suppression of tumor growth in MCF7 xenograft mice compared to single tamoxifen treatment. In conclusion, TNFα promoted tamoxifen sensitivity through the dissociation of the ERα-p53-NCOR1 complex, pointing at NCOR1 as a putative therapeutic target for overcoming tamoxifen resistance in ERα-positive breast cancer.Introduction The use of vitamin K antagonists (VKAs) in non-valvular atrial fibrillation (NVAF) is complicated d
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